Water → Cyclohexanepropanol, 2,2,6-trimethyl-.alpha.-propyl-

HRID 1446782ノート

反応式

HRID 1446782 の反応式
[CH3:1][C:2]([CH2:11][CH2:12][CH2:13][C:14]([CH3:16])=[CH2:15])=[CH:3][CH:4]=[CH:5][C:6](=[O:10])[CH2:7][CH2:8][CH3:9].P(=O)(O)(O)O.O>C1C=CC=CC=1>[CH3:15][C:14]1([CH3:16])[CH2:13][CH2:12][CH2:11][CH:2]([CH3:1])[CH:3]1[CH2:4][CH2:5][CH:6]([OH:10])[CH2:7][CH2:8][CH3:9]

参加物

5

反応物 3

HCID 962WaterHCID 1004Phosphoric AcidHCID 54331378HCID 54331378、化合物

生成物 1

HCID 116699Cyclohexanepropanol, 2,2,6-trimethyl-.alpha.-propyl-

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

反応条件

温度
20 °C

実験手順

1.66 kilograms of 8,12-dimethyltrideca-5,7,12-tri-en-4-on dissolved in 3 kilograms benzene are dropped while stirring at 10°-15° C. into 1.66 kilograms phosphoric acid and the reaction mixture is stirred for 2 hours at 20° C. and thereafter for 3 hours at 30° C. Thereupon water is added, the aqueous phase is extracted twice with benzene, the benzene extract is neutrally washed with sodium carbonate solution, and the benzene is then removed by distillation. The reaction product is purified by distillation. The yield is 1.3 kilograms 1-(2',6',6'-trimethylcyclohex-2'-enyl)-hex-1-en-3-on.

後処理

  1. additionare dropped
  2. waitfor 3 hours at 30° C
  3. extractionthe aqueous phase is extracted twice with benzene
  4. extractionthe benzene extract
  5. washis neutrally washed with sodium carbonate solution
  6. customthe benzene is then removed by distillation
  7. distillationThe reaction product is purified by distillation

出典と根拠

ORDレコード
ord-8e27e988c0f14e4a8bf1dea9d3303c47
出典データセット
uspto-grants-1982_02
特許番号
US04313855

反応ノート

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