Allylamine → HCID 20383074、化合物
反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][CH2:9][CH:8]([C:11]([O:13]C)=O)[CH2:7][C:6]=2[CH:15]=1.[CH2:16]([NH2:19])[CH:17]=[CH2:18]>C(Cl)Cl.C(O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][CH2:9][CH:8]([C:11]([NH:19][CH2:16][CH:17]=[CH2:18])=[O:13])[CH2:7][C:6]=2[CH:15]=1参加物
5
実験手順
A mixture of 500 mg of 6C, 5 ml of 2-propenamine and 25 ml of ethanol was refluxed for 18 hours. The sovlent was then stripped off and the residue was taken up in methylene chloride, triturated with hexane and cooled to give a solid. The solid was redissolved in ethanol, the solution was passed through a short silica gel column and the eluent was stripped of solvent. The residue was recrystallized from methylene chloride/hexane to give 6, as white needles, mp: 171°-171.5° C.
後処理
- temperaturewas refluxed for 18 hours
- customtriturated with hexane
- temperaturecooled
- customto give a solid
- customThe residue was recrystallized from methylene chloride/hexane
- customto give 6
出典と根拠
- ORDレコード
- ord-c8e68c6c75be44969de6710b879b7c76
- 出典データセット
- uspto-grants-1979_12
- 特許番号
- US04178380
反応ノート
読み込み中…