Triethylamine → HCID 53726423、化合物

HRID 1448078ノート

反応式

HRID 1448078 の反応式
[N:1](=[C:3]1[CH2:8][S:7][CH2:6][CH2:5][S:4]1)[OH:2].[CH3:9][N:10]([S:14][C:15]([CH3:22])([C:17](=[O:21])[CH:18]([CH3:20])[CH3:19])[CH3:16])[C:11](Cl)=[O:12].C(N(CC)CC)C>O1CCOCC1>[CH3:9][N:10]([S:14][C:15]([CH3:16])([C:17](=[O:21])[CH:18]([CH3:19])[CH3:20])[CH3:22])[C:11]([O:2][N:1]=[C:3]1[CH2:8][S:7][CH2:6][CH2:5][S:4]1)=[O:12]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 54024146N-methyl-N-(2,4-dimethyl-3-oxo-2-pentanesulfenyl)carbamoyl chlorideHCID 71364189N-1,4-Dithian-2-ylidenehydroxylamine

生成物 1

HCID 53726423HCID 53726423、化合物

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

Prepared as in Example 1 by reacting 8.0 g (0.053 m) of 2-oximino-1,4-dithiane, 15.2 g (0.058 m) of N-methyl-N-(2,4-dimethyl-3-oxo-2-pentanesulfenyl)carbamoyl chloride and 5.42 g (0.053 m) of triethylamine in 100 ml of dioxane. The product crystallized from isopropyl ether-ethyl acetate to yield 4.3 g of a white solid, (m.p. 80°-82° C.) Recrystallization raised the melting point to 85°-86° C.

後処理

  1. customPrepared as in Example 1
  2. customThe product crystallized from isopropyl ether-ethyl acetate
  3. customto yield
  4. custom4.3 g of a white solid, (m.p. 80°-82° C.) Recrystallization
  5. temperatureraised the melting point to 85°-86° C.

出典と根拠

ORDレコード
ord-b3314970f6a2492ca88cfbb8531c9eb5
出典データセット
uspto-grants-1979_12
特許番号
US04179514

反応ノート

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