Potassium Hydroxide → p-(2,4-Dimethoxybenzyloxy)aniline
反応式
[CH3:1][O:2][C:3]1[CH:20]=[C:19]([O:21][CH3:22])[CH:18]=[CH:17][C:4]=1[CH2:5][O:6][C:7]1[CH:16]=[CH:15][C:10]([NH:11]C(=O)C)=[CH:9][CH:8]=1.[OH-].[K+]>C(O)C>[CH3:1][O:2][C:3]1[CH:20]=[C:19]([O:21][CH3:22])[CH:18]=[CH:17][C:4]=1[CH2:5][O:6][C:7]1[CH:16]=[CH:15][C:10]([NH2:11])=[CH:9][CH:8]=1参加物
4
実験手順
p-(2,4-Dimethoxybenzyloxy)acetanilide (3 g, 0.01 M) in ethanol (30 ml) is treated with potassium hydroxide (3 g), then the mixture is heated under reflux for 12 hours. The solvent is removed by evaporation, the residue treated with water and extracted with ether. The ether solution is treated with charcoal, dried and concentrated to afford p-(2,4-dimethoxybenzyloxy)aniline.
後処理
- temperaturethe mixture is heated
- temperatureunder reflux for 12 hours
- customThe solvent is removed by evaporation
- additionthe residue treated with water
- extractionextracted with ether
- additionThe ether solution is treated with charcoal
- customdried
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-b8a49b87ed4243e9aa697cc303af4aa9
- 出典データセット
- uspto-grants-1979_12
- 特許番号
- US04180509
反応ノート
読み込み中…