Ammonium Hydroxide → 2-Amino-4,5-dichlorophenol

HRID 1448474

反応式

HRID 1448474 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([OH:12])[C:5]([N+:9]([O-])=O)=[CH:6][C:7]=1[Cl:8].[OH-].[NH4+].S(S([O-])=O)([O-])=O.[Na+].[Na+]>O>[Cl:1][C:2]1[CH:3]=[C:4]([OH:12])[C:5]([NH2:9])=[CH:6][C:7]=1[Cl:8]

参加物

5

反応物 3

HCID 14923Ammonium HydroxideHCID 24489Sodium DithioniteHCID 382484,5-Dichloro-2-nitrophenol

生成物 1

HCID 30154152-Amino-4,5-dichlorophenol

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

106 g of 9A was suspended in 636 ml of water. 233 ml of ammonium hydroxide was added. 239.2 g of sodium dithionite was added over a period of about two hours at such a rate that the temperature of the reaction mixture was kept at about 50° C. The mixture was stirred at room temperature for two hours. The solid product was filtered, and extracted with methanol. Evaporation of the solvent from the extract gave 3,4-dichloro-6-aminophenol (9B).

後処理

  1. customwas kept at about 50° C
  2. filtrationThe solid product was filtered
  3. extractionextracted with methanol
  4. customEvaporation of the solvent from the extract

出典と根拠

ORDレコード
ord-f08dabe03a514d858342b6359c8f71e6
出典データセット
uspto-grants-1979_12
特許番号
US04180572

関連ノート

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