Hydroxide → HCID 86750312、化合物

反応式

[CH:1]([C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][C:18]=1[N+:19]([O-:21])=[O:20])[O:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=O.[OH:22][C:23]1[NH:24][C:25](=[O:47])[CH2:26][C:27]=1[P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[OH-]>C(O)C>[O:22]=[C:23]1[NH:24][C:25](=[O:47])[CH2:26]/[C:27]/1=[CH:1]\[C:3]1[CH:4]=[C:5]([CH:16]=[CH:17][C:18]=1[N+:19]([O-:21])=[O:20])[O:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12]

参加物

実験手順

A mixture of ethyl 5-(3-formyl-4-nitrophenoxy)pentanoate (0.60 mol) and (4,5-di-hydro-2-hydroxy-5-oxo-1H-pyrrol-3-yl)triphenylphosphonium, hydroxide, inner salt (0.57 mol) in ethanol (1500 ml) was stirred and refluxed for 1 hour. The solvent was removed. The residue was stirred in methylbenzene. The resulting precipitate was filtered off, washed with methylbenzene, 2,2'-oxybispropane and dried, yielding 137.3 g (61%) of (E)-ethyl 5-[3-[(2,5-dioxo-3-pyrrolidinylidene)methyl]-4-nitrophenoxy]pentanoate; mp. 112.4° C. (interm. 1).