Ethanone, 1-(2,4,6-trimethylphenyl)- → 2-Bromo-1-mesitylethanone

HRID 1450251

反応式

HRID 1450251 の反応式
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[C:4]([CH3:9])[C:3]=1[C:10](=[O:12])[CH3:11].[Br:13]Br>C(O)(=O)C>[Br:13][CH2:11][C:10]([C:3]1[C:4]([CH3:9])=[CH:5][C:6]([CH3:8])=[CH:7][C:2]=1[CH3:1])=[O:12]

参加物

4

反応物 2

HCID 15461Ethanone, 1-(2,4,6-trimethylphenyl)-HCID 24408Bromine

生成物 1

HCID 2194802-Bromo-1-mesitylethanone

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

0.3 mol of 1-(2,4,6-trimethylphenyl)-1-ethanone are dissolved in 200 mi of glacial acetic acid and 31.8 g of bromine are added dropwise, while maintaining the reaction medium at a temperature below 10° C. After the addition, the reaction medium is allowed to return to room temperature and is left at this temperature for 2 hours. The reaction medium is then poured into 500 ml of ice-water and the aqueous phase is extracted with ethyl ether. The organic extracts are washed with saturated aqueous sodium bicarbonate solution end then with salted water, end are dried over anhydrous magnesium sulphate.

後処理

  1. additionare added dropwise
  2. temperaturewhile maintaining the reaction medium at a temperature below 10° C
  3. additionAfter the addition
  4. customto return to room temperature
  5. extractionthe aqueous phase is extracted with ethyl ether
  6. washThe organic extracts are washed with saturated aqueous sodium bicarbonate solution end
  7. dry with materialwith salted water, end are dried over anhydrous magnesium sulphate

出典と根拠

ORDレコード
ord-26eddd4c8b874c3e8ae8c1f0383ab1fd
出典データセット
uspto-grants-1997_02
特許番号
US05602132

関連ノート

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