MAGNESIUM SILICATE (synthetic) → HCID 19976958、化合物

HRID 1450642ノート

反応式

HRID 1450642 の反応式
[OH:1][CH:2]([C:5]1[O:9][N:8]=[C:7]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=2)[CH:6]=1)[CH2:3][CH3:4].C([O-])(=O)C.[Na+].[O-][Si]([O-])=O.[Mg+2].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>ClCCl>[CH3:17][O:16][C:13]1[CH:12]=[CH:11][C:10]([C:7]2[CH:6]=[C:5]([C:2](=[O:1])[CH2:3][CH3:4])[O:9][N:8]=2)=[CH:15][CH:14]=1

参加物

6

反応物 4

HCID 61680MAGNESIUM SILICATE (synthetic)HCID 517045Sodium AcetateHCID 19976898HCID 19976898、化合物HCID 178418287HCID 178418287、化合物

生成物 1

HCID 19976958HCID 19976958、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Added to 160 ml of dichloromethane were 8.07 g (34.6 mmol) of 5-(1-hydroxypropyl)-3-(4-methoxyphenyl)-isoxazole prepared in the above procedure (2), 4.83 g (58.9 mmol) of sodium acetate and 12.7 g of "Florisil" (trade mark, Wakojunyaku Inc.). While the resultant mixture was stirred vigorously, 12.7 g (58.9 mmol) pyridinium chlorochromate were added in small portions. After the mixture was stirred at room temperature for 4 hours, an insoluble material was filtered off and the solvent was distilled off. The residue was recrystallized from n-hexane, whereby 3-(4-methoxyphenyl) -5-propionylisoxazole was colorless crystals.

後処理

  1. filtrationan insoluble material was filtered off
  2. distillationthe solvent was distilled off
  3. customThe residue was recrystallized from n-hexane, whereby 3-(4-methoxyphenyl) -5-propionylisoxazole

出典と根拠

ORDレコード
ord-4a44514a0c9c44c3a1eeec8bc5b15c37
出典データセット
uspto-grants-1997_02
特許番号
US05602160

反応ノート

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