Hydrochloric Acid → HCID 178479374、化合物
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6].[ClH:11].[N:12]#[C:13][NH2:14]>C(O)C>[ClH:11].[NH:1]([C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=[O:6])[C:13]([NH2:14])=[NH:12]参加物
5
実験手順
A mixture of 3-aminobenzoic acid (Aldrich, 2.74 g, 0.02 mol), hydrochloric acid (12N, 1.66 g, 0.02 mol), and cyanamide (1.64 g, 0.04 mol) in absolute ethanol (50 mL) was heated at reflux for 16 h. The mixture was cooled and the precipitate separated by filtration. The cake was washed several times with ether and dried under vacuum to give 1.05 g (26.6%) of the title compound as an off-white amorphous powder, mp 278° C.
後処理
- temperaturewas heated
- temperatureat reflux for 16 h
- temperatureThe mixture was cooled
- customthe precipitate separated by filtration
- washThe cake was washed several times with ether
- customdried under vacuum
出典と根拠
- ORDレコード
- ord-61d0e2cc79214452bc663742e726f5a2
- 出典データセット
- uspto-grants-1997_02
- 特許番号
- US05602277
反応ノート
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