HCID 15200703、化合物 → HCID 19972869、化合物

HRID 1451701ノート

反応式

HRID 1451701 の反応式
[CH3:1][N:2]([CH3:27])[C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH:22]=[CH:21][NH:20][C:19]3[C:18](=[O:23])[C:17]4[NH:16][C:15](=[O:24])[CH:14]=[C:13]([CH3:25])[C:12]=4[C:11](=[O:26])[C:10]2=3)=[CH:5][CH:4]=1>C1(C)C(C)=CC=CC=1>[CH3:27][N:2]([CH3:1])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:22]=[CH:21][N:20]=[C:19]3[C:10]=2[C:11](=[O:26])[C:12]2[C:13]([CH3:25])=[CH:14][C:15](=[O:24])[NH:16][C:17]=2[C:18]3=[O:23])=[CH:5][CH:4]=1

参加物

3

反応物 1

HCID 15200703HCID 15200703、化合物

生成物 1

HCID 19972869HCID 19972869、化合物収率 80%

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒

実験手順

A solution of 25 mg (0.07 mmol) of 3 in xylene (60 ml) was refluxed for 16 hours while air was bubbling through the solution. After evaporation of the solvent, the residue was purified by silica gel chromatography, using ethyl acetate as eluent to yield 20 mg (80%) of 6.

後処理

  1. customwas bubbling through the solution
  2. customAfter evaporation of the solvent
  3. customthe residue was purified by silica gel chromatography

出典と根拠

ORDレコード
ord-91b37fa60f194ae0b03532e900609a18
出典データセット
uspto-grants-1997_02
特許番号
US05605905

反応ノート

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