化工社化工社 化学情報印刷レポート · 研究参考用
1,5,6,7-Tetrahydro-4H-indol-4-one → 1,5,6,7-Tetrahydro-indol-4-one oxime
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,5,6,7-Tetrahydro-4H-indol-4-one | HCID 280229 | — |
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1,5,6,7-Tetrahydro-indol-4-one oxime | HCID 915677 | — |
反応手順
A solution of 6.08 g of sodium acetate, 5.15 g of hydroxylamine hydrochloride, and 5.25 g of 4-keto-4,5,6,7-tetrahydro indole in 12 mL of water and 36 mL of ethanol was heated at 50° C. for 3 hr, quenched in water, extracted with ethyl acetate and dried over magnesium sulfate. The solvents were removed in vacuo to give a mixture of oxime isomers which was characterized by NMR and Mass spectroscopy.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05606054 |
| 出典データセット | uspto-grants-1997_02 |
| ORD ID | ord-67f58450e7b44dd5893acb47d5bfeea7 |
| 出典メモ | uspto-grants-1997_02 |