Stannous Chloride → 3-Fluoro-4-(4-methyl-[1,2,3]triazol-1-yl)-phenylamine
反応式
[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[N:11]1[CH:15]=[C:14]([CH3:16])[N:13]=[N:12]1.Cl[Sn]Cl>>[F:1][C:2]1[CH:7]=[C:6]([NH2:8])[CH:5]=[CH:4][C:3]=1[N:11]1[CH:15]=[C:14]([CH3:16])[N:13]=[N:12]1参加物
3
実験手順
1-(2-Fluoro-4-nitro-phenyl)-4-methyl-[1,2,3]-triazole (Intermediate 22) (38.3 g, 0.173 mol) and SnCl2 2H2O (200 g, 0.886 mol) were reacted as described for Intermediate 27 to give the crude title compound as a off-white solid (31.9 g), which was used directly for the next reaction.
出典と根拠
- ORDレコード
- ord-0d0248ec50214d13bce37fbc45e37923
- 出典データセット
- uspto-grants-2009_01
- 特許番号
- US07473699B2
反応ノート
読み込み中…