化工社化工社 化学情報印刷レポート · 研究参考用
3-Fluorobenzenesulfonyl Chloride → N-(3-cyano-1H-indazol-5-yl)-3-fluorobenzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Fluorobenzenesulfonyl Chloride | HCID 2734258 | — |
| 反応物 | 5-Amino-1H-indazole-3-carbonitrile | HCID 22567303 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | N-(3-cyano-1H-indazol-5-yl)-3-fluorobenzenesulfonamide | HCID 10064331 | 84.3% |
反応手順
N-(3-Cyano-1H-indazol-5-yl)-3-fluorobenzenesulfonamide can be obtained as described in Example 2 from 0.6 g of 5-amino-3-cyano-1H-indazole, 12 ml of pyridine and 0.73 g of 3-fluorobenzenesulfonyl chloride. 1 g of N-(3-cyano-1H-indazol-5-yl)-3-fluorobenzenesulfonamide is thus obtained in the form of a yellow solid melting at 227° C. (analysis C14H9FN4O2S % calculated C, 53.16; H, 2.87; F, 6.01; N, 17.71; O, 10.12; S, 10.14% found C, 52.86; H, 2.63; F, 5.67; N, 16.04).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07473701B2 |
| 出典データセット | uspto-grants-2009_01 |
| ORD ID | ord-a0f1c1d559d7441da8a91da435bb53a7 |
| 出典メモ | uspto-grants-2009_01 |