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2-Methanesulfonylbenzene-1-sulfonyl chloride → HCID 178504719、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Methanesulfonylbenzene-1-sulfonyl chloride | HCID 2735178 | — |
| 反応物 | HCID 178507363 | HCID 178507363 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | HCID 178504719 | HCID 178504719 | 82.4% |
反応手順
N-(3-Iodo-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide can be obtained as described in Example 2 from 25.7 g of 5-amino-3-iodo-1H-indazole, 440 ml of pyridine and 25.3 g of 2-(methylsulfonyl)benzenesulfonyl chloride. 39 g of N-(3-iodo-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide are thus obtained in the form of a brown solid (mass analysis: Cl: m/z 478 (M+H)+, m/z 495 (M+NH4)+, m/z 260 (base peak)).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07473701B2 |
| 出典データセット | uspto-grants-2009_01 |
| ORD ID | ord-aa174d0203294099a0a2428c685a01fd |
| 出典メモ | uspto-grants-2009_01 |