HCID 58762434、化合物 → 1-Cyclopentyl-2-(5-methoxy-indan-1-yl)-ethanone

反応式

N1C=CC=CC=1S[C:8](=[O:21])[CH2:9][CH:10]1[C:18]2[C:13](=[CH:14][C:15]([O:19][CH3:20])=[CH:16][CH:17]=2)[CH2:12][CH2:11]1.N1C=CC=CC=1SC(=O)CC[C:32]1[CH2:37][CH2:36][CH2:35][CH2:34]C=1>>[CH:34]1([C:8](=[O:21])[CH2:9][CH:10]2[C:18]3[C:13](=[CH:14][C:15]([O:19][CH3:20])=[CH:16][CH:17]=3)[CH2:12][CH2:11]2)[CH2:35][CH2:36][CH2:37][CH2:32]1

参加物

反応物 2

HCID 58762434HCID 58762434、化合物

HCID 86600106(5-Methoxy-indan-1-yl)-thioacetic Acid S-pyridin-2-yl Ester

生成物 1

HCID 688674851-Cyclopentyl-2-(5-methoxy-indan-1-yl)-ethanone

実験手順

The title compound was prepared as described in Step 4 of Example A(13), where (5-Methoxy-indan-1-yl)-thioacetic acid S-pyridin-2-yl ester (from Step 3) was substituted in place of 3-Cyclohex-1-enyl-thiopropionic acid S-pyridin-2-yl ester. 1H NMR (CDCl3): δ 1.55-1.85 (br m, 9H), 2.39 (m, 1H), 2.60 (dd, 1H, J=17.2, 8.6 Hz), 2.80-2.92 (m, 4H), 3.59 (m, 1H), 3.78 (s, 3H), 6.70 (d, 1H, J=8.3 Hz), 6.77 (s, 1H), 7.02 (d, 1H, J=8.3 Hz).

出典と根拠

ORDレコード: ord-203e12ddefb846d4aa1d2fc2ca926021
出典データセット: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07473790B2

反応ノート

読み込み中…