HCID 22498708、化合物 → HCID 178499184、化合物

HRID 1453888ノート

反応式

HRID 1453888 の反応式
[CH2:1]([O:8][C:9]1[C:10]([C:18]([OH:20])=O)=[N:11][NH:12][C:13]=1[C:14]([O:16][CH3:17])=[O:15])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH:27]([OH:31])[CH2:28][NH:29][CH3:30].N1C=CC=C(C(O)CNC)C=1>>[CH2:1]([O:8][C:9]1[C:13]([C:14]([O:16][CH3:17])=[O:15])=[N:12][NH:11][C:10]=1[C:18]([N:29]([CH2:28][CH:27]([OH:31])[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][N:21]=1)[CH3:30])=[O:20])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 3

HCID 22498708HCID 22498708、化合物HCID 224987342-(Methylamino)-1-(pyridin-3-yl)ethan-1-olHCID 57528495Methyl 4-benzyloxy-3-carboxy-1H-pyrazole-5-carboxylate

生成物 1

HCID 178499184HCID 178499184、化合物

実験手順

The title compound was prepared from methyl 4-benzyloxy-3-carboxy-1H-pyrazole-5-carboxylate (prepared as in Example 31, Step 1) using a procedure similar to that described in Example 31, Step 2, except that 1-(2-pyridyl)-2-methylaminoethanol (prepared by the methods of Tsushima, S., et al., EP 278621 and Cudahy, M. M., et al., WO 2003059911) was used in place of 1-(3-pyridyl)-2-methylaminoethanol. ES MS (M+1)=410.

後処理

  1. customprepared by the methods of Tsushima, S

出典と根拠

ORDレコード
ord-0439cdb7e8014675a61b1feffbf0df68
出典データセット
uspto-grants-2009_01
特許番号
US07476666B2

反応ノート

読み込み中…