Ethylamine → 29526-66-7

HRID 1454271ノート

反応式

HRID 1454271 の反応式
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[N+:11]([O-])=O.[CH2:14]([NH2:16])[CH3:15]>C(Cl)Cl>[NH2:11][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:2]=1[CH3:1])[C:6]([NH:16][CH2:14][CH3:15])=[O:7]

参加物

4

反応物 2

HCID 6341EthylamineHCID 663234-Methyl-3-nitrobenzoyl chloride

生成物 1

HCID 1260797429526-66-7

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

4-methyl-3-nitro-benzoyl chloride (1.0 g, 5.0 mmol) was dissolved in DCM, and the solution was cooled to 0EC. Ethyl amine (2.0M in THF, 5.0 mL, 10 mmol) was added dropwise to the acid chloride, and the reaction stirred at 0EC for 5 min. The ice bath was removed and reaction continued to stir for 3. The solution was washed with brine, dried (Na2SO4), and concentrated in vacuo. The resulting aniline (0.75 g) was used without further purification.

後処理

  1. temperaturethe solution was cooled to 0EC
  2. customThe ice bath was removed
  3. customreaction
  4. stirringto stir for 3
  5. washThe solution was washed with brine
  6. dry with materialdried (Na2SO4)
  7. concentrationconcentrated in vacuo
  8. customThe resulting aniline (0.75 g) was used without further purification

出典と根拠

ORDレコード
ord-d5e2d6173e7144c698fdce63bee20613
出典データセット
uspto-grants-2009_01
特許番号
US07479495B2

反応ノート

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