HCID 86608644、化合物 → HCID 69016616、化合物
反応式
[C:1]1([CH:7]2[CH2:16][CH2:15][C:14]3[C:9](=[CH:10][CH:11]=[C:12]([O:17][C:18]4[N:23]=[CH:22][C:21]([NH2:24])=[CH:20][CH:19]=4)[CH:13]=3)[O:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.N1CCC(C(O)=O)CC1.C([O:38][C:39](=[O:50])[CH2:40][CH2:41][C@H:42]([NH:46]C(O)=O)[C:43](O)=[O:44])(C)(C)C>>[NH2:46][C@H:42]([C:43](=[O:44])[NH:24][C:21]1[CH:22]=[N:23][C:18]([O:17][C:12]2[CH:13]=[C:14]3[C:9](=[CH:10][CH:11]=2)[O:8][CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:16][CH2:15]3)=[CH:19][CH:20]=1)[CH2:41][CH2:40][C:39]([OH:50])=[O:38]参加物
3
実験手順
(S)-4-Amino-4-[6-(2-phenylchroman-6-yloxy)pyridin-3-ylcarbamoyl]butyric acid was prepared as described for piperidine-4-carboxylic acid [6-(2-phenyl-chroman-6-yloxy)pyridine-3-yl]amine in Example 19 a) and b) but replacing N-(tert-butoxycarbonyl)isonipecotic acid with (S)-2-carboxyaminopentanedioic acid 5-tert-butyl ester.
出典と根拠
- ORDレコード
- ord-df4381254be64c7bb909dc50f37e5993
- 出典データセット
- uspto-grants-2009_01
- 特許番号
- US07482340B2
反応ノート
読み込み中…