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1,2,3,6-Tetrahydropyridine → 1-(6-(2-Butynyloxy)pyrimidin-4-yl)-1,2,3,6-tetrahydropyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2,3,6-Tetrahydropyridine | HCID 12750 | — |
| 反応物 | 4-(2-Butynyloxy)-6-chloropyrimidine | HCID 12137602 | — |
| 生成物 | 1-(6-(2-Butynyloxy)pyrimidin-4-yl)-1,2,3,6-tetrahydropyridine | HCID 57819812 | 100.9% |
反応手順
0.3 g of 4-chloro-6-(2-butynyloxy)pyrimidine and 0.41 g of 1,2,3,6-tetrahydropyridine were mixed and left for 2 hours at room temperature. The reaction mixture was subjected to silica gel column chromatography to obtain 0.38 g of 1-(6-(2-butynyloxy)pyrimidin-4-yl)-1,2,3,6-tetrahydropyridine (hereinafter, referred to as Compound (54)).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732448B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-d976352f2ebb4c96abede001169aa40a |
| 出典メモ | uspto-grants-2010_06 |