化工社化工社 化学情報印刷レポート · 研究参考用
1,2,3,6-Tetrahydropyridine → 1-(4-(2-Pentynyloxy)pyrimidin-6-yl)pyridine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2,3,6-Tetrahydropyridine | HCID 12750 | — |
| 反応物 | 4-Chloro-6-(2-pentenyloxy)pyrimidine | HCID 86607468 | — |
| 生成物 | 1-(4-(2-Pentynyloxy)pyrimidin-6-yl)pyridine | HCID 66594956 | 63.1% |
反応手順
0.3 g of 4-chloro-6-(2-pentenyloxy)pyrimidine and 0.25 g of 1,2,3,6-tetrahydropyridine were mixed and left for 3 hours at room temperature. The reaction mixture was subjected to silica gel column chromatography to obtain 0.23 g of 1-(4-(2-pentynyloxy)pyrimidin-6-yl)pyridine (hereinafter, referred to as Compound (55)).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732448B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-640072bca9d8490abb6427decdcf1384 |
| 出典メモ | uspto-grants-2010_06 |