Sulfuric Acid → Xanthone-2-carboxylic acid

HRID 1456684ノート

反応式

HRID 1456684 の反応式
[C:1]([C:4]1[CH:19]=[CH:18][C:7]([O:8][C:9]2[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=2[C:11]([OH:13])=O)=[CH:6][CH:5]=1)([OH:3])=[O:2].S(=O)(=O)(O)O>O>[O:13]=[C:11]1[C:6]2[CH:5]=[C:4]([C:1]([OH:3])=[O:2])[CH:19]=[CH:18][C:7]=2[O:8][C:9]2[C:10]1=[CH:14][CH:15]=[CH:16][CH:17]=2

参加物

4

反応物 2

HCID 1118Sulfuric AcidHCID 226650732-(4-Carboxyphenoxy)benzoic acid

生成物 1

HCID 473472Xanthone-2-carboxylic acid収率 87.6%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
80 °C

実験手順

A mixture of 29.9 g (0.11 mol) of 2-(4-carboxyphenoxy)benzoic acid (Example 10e) and 250 ml of concentrated sulfuric acid is heated at 80° C. for one hour. The resulting solution is then poured onto about 2.5 litres of water and the mixture is stirred vigorously for 30 minutes. The product which has precipitated is filtered off, washed with water and dried under a high vacuum. 23.15 g (85%) of 9-oxo-9H-xanthene-2-carboxylic acid, melting point>280° C., result as a beige. powder.

後処理

  1. customThe product which has precipitated
  2. filtrationis filtered off
  3. washwashed with water
  4. customdried under a high vacuum

出典と根拠

ORDレコード
ord-00d4fca321b643d1b5a790d7179910a6
出典データセット
uspto-grants-1998_12
特許番号
US05844024

反応ノート

読み込み中…