Phosphoric Acid → HCID 54233355、化合物
反応式
[F:1][C:2]1[CH:11]=[C:10]([F:12])[CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][CH2:6][C:7]2=[O:13].O.[C:15]([OH:19])(=[O:18])[CH:16]=O.P(=O)(O)(O)O>O>[F:1][C:2]1[CH:11]=[C:10]([F:12])[CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][C:6](=[CH:16][C:15]([OH:19])=[O:18])[C:7]2=[O:13]参加物
5
反応条件
- 温度
- 90 °C
実験手順
A mixture of 5,7-difluoro-3,4-dihydro-1(2H)-naphthalenone (3.2 g), glyoxylic acid monohydrate (1.6 g) and 85% phosphoric acid (3 ml) was heated with stirring at 90° C. for four hours. After cooling, water was added to the reaction solution, and the precipitated crystals were collected by filtration, washed with water, and dried to give (5,7-difluoro-3,4-dihydro-1-oxo-2(1H)-naphthalenylidene)acetic acid (4.2).
後処理
- temperaturewas heated
- temperatureAfter cooling
- filtrationthe precipitated crystals were collected by filtration
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-4da6063f6f8c4be093017d0d15b90d54
- 出典データセット
- uspto-grants-1998_12
- 特許番号
- US05847159
反応ノート
読み込み中…