(2,6-Dichloropyridin-3-YL)methanamine → S-methyl-N-(6-chloro-3-pyridyl)-N-ethyl-N'-methylisothiourea
反応式
Cl[C:2]1C(CN)=CC=C(Cl)N=1.[Cl:11][C:12]1[N:17]=[CH:16][C:15]([N:18]([CH2:23][CH3:24])[C:19]([NH:21][CH3:22])=[S:20])=[CH:14][CH:13]=1.ClC1N=CC(N(C)C(NC)=S)=CC=1>>[CH3:2][S:20][C:19](=[N:21][CH3:22])[N:18]([C:15]1[CH:16]=[N:17][C:12]([Cl:11])=[CH:13][CH:14]=1)[CH2:23][CH3:24]参加物
4
実験手順
The reaction procedure of Example 59 (2) was repeated except that N-(6-chloro-3-pyridyl)-N-ethyl-N'-methylthiourea was used in lieu of N-(6-chloro-3-pyridyl)-N-methyl-N'-methylthiourea to give S-methyl-N-(6-chloro-3-pyridyl)-N-ethyl-N'-methylisothiourea as a pale yellow oil.
出典と根拠
- ORDレコード
- ord-ea979e14476c4367b1848d28b09b9d2a
- 出典データセット
- uspto-grants-1998_12
- 特許番号
- US05849768
反応ノート
読み込み中…