化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Peroxide → 4-Methoxyimino-5-methylthiochroman-6-carboxylic acid-1,1-dioxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Peroxide | HCID 784 | — |
| 反応物 | Ethyl Acetate | HCID 8857 | — |
| 反応物 | 4-Methoxyimino-5,8-dimethyl-6-(1-ethyl-5-n-propanesulfonyloxypyrazol-4-yl)carbonylthiochroman-1,1-dioxide | HCID 53795658 | — |
| 反応物 | 4-Methoxyimino-5-methylthiochroman-6-carboxylic acid | HCID 53997679 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 4-Methoxyimino-5-methylthiochroman-6-carboxylic acid-1,1-dioxide | HCID 53971540 | 97% |
反応手順
1.0 Gram (4.0 mmol) of the 4-methoxyimino-5-methylthiochroman-6-carboxylic acid obtained in the above (2) was reacted with 1.3 g (12 mmol) of a 30% hydrogen peroxide aqueous solution in 5 ml of acetic acid at 100° C. for 1 hour. Ethyl acetate was added to the reaction product, and the mixture was washed with a saturated sodium chloride aqueous solution and then dried over sodium sulfate. The solvent was distilled off to give 1.1 g (yield 97%) of 4-methoxyimino-5-methylthiochroman-6-carboxylic acid-1,1-dioxide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05849926 |
| 出典データセット | uspto-grants-1998_12 |
| ORD ID | ord-8c6cd4df0e944072bdac1909224c6ce9 |
| 出典メモ | uspto-grants-1998_12 |