Hydrochloric Acid → HCID 22097029、化合物
反応式
[Cl:1][C:2]1[C:3]([N:17]([CH3:23])[S:18]([CH2:21][CH3:22])(=[O:20])=[O:19])=[C:4]2[C:9](=[CH:10][C:11]=1[Cl:12])[N:8]=[C:7]([O:13]C)[C:6]([O:15]C)=[N:5]2.Cl>O1CCOCC1>[Cl:1][C:2]1[C:3]([N:17]([CH3:23])[S:18]([CH2:21][CH3:22])(=[O:20])=[O:19])=[C:4]2[C:9](=[CH:10][C:11]=1[Cl:12])[NH:8][C:7](=[O:13])[C:6](=[O:15])[NH:5]2参加物
4
実験手順
A mixture of N-(6,7-dichloro-2,3-dimethoxyquinoxalin-5-yl)-N-(methyl)-ethanesulphonamide (150 mg, 0.39 mmol), 2M hydrochloric acid (4 ml) and dioxane (8 ml) was heated at reflux for 16 hours, cooled, and concentrated under reduced pressure. The solid residue was suspended in water, filtered off, and washed with water and ether to give the title compound (140 mg, 99%) as a white solid, m.p. >300° C.