4-chloro-N-cyclohexyl-2-nitroaniline → 4-Chloro-N1-cyclohexylbenzene-1,2-diamine

HRID 1458838ノート

反応式

HRID 1458838 の反応式
[Cl:1][C:2]1[CH:14]=[CH:13][C:5]([NH:6][CH:7]2[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]2)=[C:4]([N+:15]([O-])=O)[CH:3]=1>C(O)C.[Ni]>[NH2:15][C:4]1[CH:3]=[C:2]([Cl:1])[CH:14]=[CH:13][C:5]=1[NH:6][CH:7]1[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1

参加物

4

反応物 1

HCID 28372924-chloro-N-cyclohexyl-2-nitroaniline

生成物 1

HCID 220971504-Chloro-N1-cyclohexylbenzene-1,2-diamine収率 103.7%

試薬・触媒・溶媒 2

HCID 935Nickel触媒HCID 702Ethanol溶媒

実験手順

41.6 g (0.16 mol) of 4-chloro-N-cyclohexyl-2-nitroaniline were dissolved in 400 ml of ethanol and, after addition of 4.2 g of Raney nickel, hydrogenated under 1 bar at 25° C. The mixture was then filtered and the filtrate was concentrated under reduced pressure to yield 37.3 g (100%) of the product.

後処理

  1. customat 25° C
  2. filtrationThe mixture was then filtered
  3. concentrationthe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-dbadf08829524f8487149ce4831606de
出典データセット
uspto-grants-1998_12
特許番号
US05852017

反応ノート

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