4-Methyl-2-(propylamino)pyridine hydrochloride → HCID 178456746、化合物

反応式

C(O)(=O)C.C(N=C1CC(C)CCN1)C.[ClH:15].[CH3:16][C:17]1[CH:22]=[CH:21][N:20]=[C:19]([NH:23][CH2:24][CH2:25][CH3:26])[CH:18]=1>>[ClH:15].[CH3:16][CH:17]1[CH2:22][CH2:21][NH:20][C:19](=[N:23][CH2:24][CH2:25][CH3:26])[CH2:18]1

参加物

反応物 2

HCID 184284624-Methyl-2-(propylamino)pyridine hydrochloride

HCID 178476385HCID 178476385、化合物

生成物 1

HCID 178456746HCID 178456746、化合物

実験手順

The method of preparation of 2-(ethylimino)-4-methylpiperidine acetate was used to convert 4-methyl-2-(propylamino)pyridine hydrochloride to the title compound The product was obtained as a clear colorless oil which crystallized under EtOAc. The analysis of the product was found to be consistent with the proposed structure. MH+=155; 1H NMR (D2O): 3.45-3.20 (m, 2H); 3.05 (t, J=6 Hz, 2H); 2.60-2.45 (m, 1H); 2.20-2.00 (m, 1.95-1.70 (m, 2H); 1.60-1.40 (m, 2H); 1.40-1.25 (m, 1H); 0.90 (d, J=6 Hz, 3H); 0.80 (t, J=6 Hz, 3H).

出典と根拠

ORDレコード: ord-3f4e78b09d2f43a88bd2fb82a781d973
出典データセット: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05854234

反応ノート

読み込み中…

参加物