5-Bromo-2,4-difluorobenzenesulfonamide → 5-[7-Cyclopropyl-5-(3,4-dichloro-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-2,4-difluoro-benzenesulfonamide

反応式

[Br:23][c:24]1[c:25]([F:35])[cH:26][c:27]([F:34])[c:28]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:29]1.[CH:1]1([c:4]2[cH:5][c:6](-[c:15]3[cH:16][c:17]([Cl:22])[c:18]([Cl:21])[cH:19][cH:20]3)[n:7][c:8]3[n:9]2[n:10][cH:11][c:12]3[C:13]#[CH:14])[CH2:2][CH2:3]1>>[CH:1]1([c:4]2[cH:5][c:6](-[c:15]3[cH:16][c:17]([Cl:22])[c:18]([Cl:21])[cH:19][cH:20]3)[n:7][c:8]3[n:9]2[n:10][cH:11][c:12]3[C:13]#[C:14][c:24]2[c:25]([F:35])[cH:26][c:27]([F:34])[c:28]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:29]2)[CH2:2][CH2:3]1

参加物

反応物 2

HCID 27732955-Bromo-2,4-difluorobenzenesulfonamide

HCID 866080507-Cyclopropyl-5-(3,4-dichloro-phenyl)-3-ethynyl-pyrazolo[1,5-a]pyrimidine

生成物 1

HCID 670009105-[7-Cyclopropyl-5-(3,4-dichloro-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-2,4-difluoro-benzenesulfonamide

出典と根拠

ORDレコード: ord-a5393d8fabb24400b7c5ac92200c584c
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…