Triethylamine → HCID 19981929、化合物

HRID 1460492ノート

反応式

HRID 1460492 の反応式
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[OH:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][N:10]=1.C(N(CC)CC)C>ClCCl>[CH3:1][S:2]([O:6][CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][N:10]=1)(=[O:4])=[O:3]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 154753442-(Pyrimidin-4-yl)ethanol

生成物 1

HCID 19981929HCID 19981929、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

A solution of methanesulphonyl chloride (137 mg) in dichloromethane (2 ml) was added to a solution of 4-(2-hydroxyethyl)pyrimidine (124 mg) (prepared by the method of C. G. Overberger and I. C. Kogon, JACS, 76, 1879 (1954)) and triethylamine (121 mg) in dichloromethane (10 ml), the mixture stirred at room temperature for 3 hours and evaporated under reduced pressure to give the crude title compound as a pale yellow oil which was used directly in Example 10 without further purification.

後処理

  1. customprepared by the method of C
  2. customevaporated under reduced pressure

出典と根拠

ORDレコード
ord-5ca7e4b745864d64be87d29d6ffcf93d
出典データセット
uspto-grants-1991_12
特許番号
US05071844

反応ノート

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