1-Octanol → 4-Octyloxy-3-pyrrolin-2-one
反応式
[CH3:1][O:2][C:3]1[CH2:7][NH:6][C:5](=[O:8])[CH:4]=1.CS(O)(=O)=O.[CH2:14](O)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]C>>[CH2:1]([O:2][C:3]1[CH2:7][NH:6][C:5](=[O:8])[CH:4]=1)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]参加物
4
反応条件
- 温度
- 100 °C
実験手順
A mixture of 4-methoxy-3-pyrrolin-2-one (3 g), 1-octanol (7.4 ml) and methanesulfonic acid (0.2 g) were heated at 100° C. for 2 hours under reduced pressure (40 mbars). The product was chromatographed on silica gel, eluting with 2% methanol in methylene chloride, to give 4-octyloxy-3-pyrrolin-2-one.
後処理
- customThe product was chromatographed on silica gel
- washeluting with 2% methanol in methylene chloride
出典と根拠
- ORDレコード
- ord-9be0502d1b17430a81781c8984463853
- 出典データセット
- uspto-grants-1991_12
- 特許番号
- US05072006
反応ノート
読み込み中…