Ammonia → 3,5-Dichloro-2,4-difluorobenzamide
反応式
[NH3:1].[Cl:2][C:3]1[C:4]([F:14])=[C:5]([CH:9]=[C:10]([Cl:13])[C:11]=1[F:12])[C:6](F)=[O:7]>O>[Cl:2][C:3]1[C:4]([F:14])=[C:5]([CH:9]=[C:10]([Cl:13])[C:11]=1[F:12])[C:6]([NH2:1])=[O:7]参加物
4
実験手順
620 ml of concentrated aqueous ammonia solution and 600 ml of water are initially introduced, 458 g (2 moles) of 3,5-dichloro-2,4-difluorobenzoyl fluoride are added dropwise at 40°-50°, and then the mixture is stirred at 50° for 30 minutes. The precipitate is filtered off with suction, washed with water and dried. 408 g (90% of theory) of 3,5-dichloro-2,4-difluorobenzamide of melting point 163°-164° are obtained.
後処理
- filtrationThe precipitate is filtered off with suction
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-0676c9de1d9f4f1d9a0eeb9394275311
- 出典データセット
- uspto-grants-1991_12
- 特許番号
- US05072038
反応ノート
読み込み中…