Water → 4-chloro-N-hexadecyl-N-methyl-3-nitrobenzenesulfonamide

HRID 1460943ノート

反応式

HRID 1460943 の反応式
[CH2:1]([NH:17][S:18]([C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([N+:28]([O-:30])=[O:29])[CH:22]=1)(=[O:20])=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[C:31](=O)([O-])[O-].[K+].[K+].COS(OC)(=O)=O.O>CC(C)=O>[CH3:31][N:17]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[S:18]([C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[C:23]([N+:28]([O-:30])=[O:29])[CH:22]=1)(=[O:19])=[O:20]

参加物

6

反応物 4

HCID 962WaterHCID 6497Dimethyl SulfateHCID 11430Potassium CarbonateHCID 14324551HCID 14324551、化合物

生成物 1

HCID 41628334-chloro-N-hexadecyl-N-methyl-3-nitrobenzenesulfonamide

試薬・触媒・溶媒 1

HCID 180Acetone溶媒2 回

実験手順

N-Hexadecyl-3-nitro-4-chlorobenzenesulfonamide (170 grams) was dissolved in 640 ml of acetone. 79 grams of potassium carbonate, 6 ml of polyethylene glycol and 71 grams of dimethylsulfate were added and the mixture was heated under reflux for a period of 5 hours. Acetone (240 ml) was then added and 870 ml of water was added dropwise at 40° C. and crystals precipitated out on cooling the mixture to room temperature. The crystals were recovered by filtration, washed with water and methanol and then dried.

後処理

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for a period of 5 hours
  3. customcrystals precipitated out
  4. filtrationThe crystals were recovered by filtration
  5. washwashed with water and methanol
  6. customdried

出典と根拠

ORDレコード
ord-787ec1cac1714427aee47230d32627b3
出典データセット
uspto-grants-1991_12
特許番号
US05073473

反応ノート

読み込み中…