Chromic Acid → 4,4-Diphenylnon-8-en-3-one

HRID 1461149

反応式

HRID 1461149 の反応式
[C:1]1([C:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)([CH2:12][CH2:13][CH2:14][CH:15]=[CH2:16])[CH:8]([OH:11])[CH2:9][CH3:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cr](O)(O)(=O)=O>CC(C)=O>[C:17]1([C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)([CH2:12][CH2:13][CH2:14][CH:15]=[CH2:16])[C:8](=[O:11])[CH2:9][CH3:10])[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

参加物

4

反応物 2

HCID 24425Chromic AcidHCID 199815114,4-Diphenylnon-8-en-3-ol

生成物 1

HCID 199815084,4-Diphenylnon-8-en-3-one収率 78.8%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

One hundred seventy milligrams of 4,4-diphenylnon-8-en-3-ol was dissolved in acetone (10 ml), and then treated with 2.7M chromic acid solution (0.04 ml). After 10 min, the excess oxidant was destroyed with isopropanol, and the mixture was diluted with ether (20 ml). Filtration through a pad of celite and concentration yielded 133 mg of 4,4-diphenylnon-8-en-3-one, as an amorphous white solid.

後処理

  1. customthe excess oxidant was destroyed with isopropanol
  2. additionthe mixture was diluted with ether (20 ml)
  3. filtrationFiltration
  4. concentrationthrough a pad of celite and concentration

出典と根拠

ORDレコード
ord-ed73cb74f4f64592b7d42a4b31c17767
出典データセット
uspto-grants-1991_12
特許番号
US05073629

関連ノート

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