Succinamide → 1-(2-Bromoethyl)pyrrolidine-2,5-dione

HRID 1461416

反応式

HRID 1461416 の反応式
[C:1]([NH2:8])(=[O:7])[CH2:2][CH2:3][C:4](N)=[O:5].[Br:9][CH:10](Br)[CH3:11].C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[Br:9][CH2:10][CH2:11][N:8]1[C:1](=[O:7])[CH2:2][CH2:3][C:4]1=[O:5]

参加物

5

反応物 3

HCID 8036SuccinamideHCID 112011,1-DibromoethaneHCID 11430Potassium Carbonate

生成物 1

HCID 135613951-(2-Bromoethyl)pyrrolidine-2,5-dione

試薬・触媒・溶媒 1

HCID 6569Methyl Ethyl Ketone溶媒

実験手順

49.5 g of succinamide was dissolved in 750 ml of 2-butanone under heating. 187.9 g of dibromoethane and 138 g of anhydrous potassium carbonate were added to the solution and the mixture was heated under reflux for 9.5 h.

後処理

  1. temperatureunder heating
  2. temperaturethe mixture was heated
  3. temperatureunder reflux for 9.5 h.

出典と根拠

ORDレコード
ord-cea0d1dc653d4b7d987b3ec6529e1f87
出典データセット
uspto-grants-1991_12
特許番号
US05075335

関連ノート

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