Potassium glycinate → Oleylmethyldihydroxyethylammonium glycinate

HRID 1461636ノート

反応式

HRID 1461636 の反応式
[Cl-].[CH2:2]([CH2:20][NH2+:21][CH2:22][CH:23]([OH:25])[OH:24])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19].NCC([O-])=O.[K+]>C(O)C(C)C>[NH2:21][CH2:22][C:23]([O-:25])=[O:24].[CH2:2]([CH2:20][NH2+:21][CH2:22][CH:23]([OH:25])[OH:24])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

参加物

4

反応物 2

HCID 23673715Potassium glycinateHCID 86745345Oleylmethyldihydroxyethylammonium chloride

生成物 1

HCID 86745343Oleylmethyldihydroxyethylammonium glycinate収率 193.1%

試薬・触媒・溶媒 1

HCID 6560Isobutanol溶媒

実験手順

A four-necked flask fitted with stirrer and condenser means was charged with 40.5 g of oleylmethyldihydroxyethylammonium chloride, 13 g of potassium glycinate and 200 g of isobutyl alcohol and the reaction was conducted at 40°-50° C. in an atmosphere of nitrogen gas introduced at a low flow rate for 6 hours. The precipitate was then collected by filtration and washed with 30 ml of isobutyl alcohol. The filtrate and the washings were combined and concentrated under reduced pressure. The residue was dissolved in 200 g of toluene and filtered. The filtrate was then concentrated to give 43.1 g (theoretical yield 44.4 g) of oleylmethyldihydroxyethylammonium glycinate as a waxy product. The elemental analysis and infrared absorption data are given below.

後処理

  1. customA four-necked flask fitted with stirrer and condenser means
  2. customwas conducted at 40°-50° C. in an atmosphere of nitrogen gas
  3. additionintroduced at a low flow rate for 6 hours
  4. filtrationThe precipitate was then collected by filtration
  5. washwashed with 30 ml of isobutyl alcohol
  6. concentrationconcentrated under reduced pressure
  7. dissolutionThe residue was dissolved in 200 g of toluene
  8. filtrationfiltered
  9. concentrationThe filtrate was then concentrated

出典と根拠

ORDレコード
ord-03d8183a1c0442c08c4699066a63a5f4
出典データセット
uspto-grants-1991_12
特許番号
US05076828

反応ノート

読み込み中…