Tert-Butylamine → HCID 19979380、化合物
反応式
[CH:1]([C:4]1[C:9]([N:10]=[C:11]=[S:12])=[C:8]([CH:13]([CH3:15])[CH3:14])[CH:7]=[C:6]([O:16][C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)[N:5]=1)([CH3:3])[CH3:2].[C:24]([NH2:28])([CH3:27])([CH3:26])[CH3:25]>C1(C)C=CC=CC=1>[C:24]([NH:28][C:11]([NH:10][C:9]1[C:4]([CH:1]([CH3:2])[CH3:3])=[N:5][C:6]([O:16][C:17]2[CH:18]=[CH:19][C:20]([Cl:23])=[CH:21][CH:22]=2)=[CH:7][C:8]=1[CH:13]([CH3:15])[CH3:14])=[S:12])([CH3:27])([CH3:26])[CH3:25]参加物
4
実験手順
8.15 g of 2,4-diisopropyl-6-(4-chlorophenoxy)-pyrid-3-yl isothiocyanate are diluted with 30 ml of toluene, and 2.0 g of tert.-butylamine are added dropwise. The reaction mixture is then further stirred for 2 hours at approximately +60° C. The reaction mixture is concentrated and hexane is added to the residue. The resulting solid is filtered off and subsequently washed with hexane. 1-tert.-Butyl-3-[2,4-diisopropyl-6-(4-chlorophenoxy)-pyrid-3-yl]-thiourea is obtained in the form of colourless crystals, m.p. 165°-167° C.