2-Chlorobenzamide → N-(2,4-Difluoro-3,5-dichlorophenyl)-N'-(2-chlorobenzoyl)-urea

HRID 1462013ノート

反応式

HRID 1462013 の反応式
[F:1][C:2]1[C:7]([Cl:8])=[C:6]([F:9])[C:5]([Cl:10])=[CH:4][C:3]=1[N:11]=[C:12]=[O:13].[Cl:14][C:15]1[CH:23]=[CH:22][CH:21]=[CH:20][C:16]=1[C:17]([NH2:19])=[O:18]>C1(C)C(C)=CC=CC=1>[F:1][C:2]1[C:7]([Cl:8])=[C:6]([F:9])[C:5]([Cl:10])=[CH:4][C:3]=1[NH:11][C:12]([NH:19][C:17](=[O:18])[C:16]1[CH:20]=[CH:21][CH:22]=[CH:23][C:15]=1[Cl:14])=[O:13]

参加物

4

反応物 2

HCID 691112-ChlorobenzamideHCID 140475992,4-Difluoro-3,5-dichlorophenyl isocyanate

生成物 1

HCID 13051730N-(2,4-Difluoro-3,5-dichlorophenyl)-N'-(2-chlorobenzoyl)-urea

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒

実験手順

A mixture of 9.0 gm (0.040 mol) of 2,4-difluoro-3,5-dichlorophenyl isocyanate, 6.5 gm (0.042 mol) of 2-chlorobenzamide, and 100 ml of xylene was boiled for five hours under reflux. It was then allowed to cool, and the product which precipitated was removed by suction filtration and dried.

後処理

  1. temperatureunder reflux
  2. temperatureto cool
  3. customthe product which precipitated
  4. customwas removed by suction filtration
  5. customdried

出典と根拠

ORDレコード
ord-dd590b7df1594f09b8351ea1e34afe0c
出典データセット
uspto-grants-1984_07
特許番号
US04457943

反応ノート

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