Morpholine → HCID 20454114、化合物

HRID 1462203ノート

反応式

HRID 1462203 の反応式
[O:1]1[CH2:6][C:5](=S)[NH:4][C:3](=[O:8])[NH:2]1.[NH:9]1[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1>>[N:9]1([C:5]2[CH2:6][O:1][NH:2][C:3](=[O:8])[N:4]=2)[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1

参加物

3

反応物 2

HCID 8083MorpholineHCID 30069082H-1,2,4-Oxadiazin-3(4H)-one, dihydro-5-thioxo-

生成物 1

HCID 20454114HCID 20454114、化合物収率 74%

実験手順

To a solution of 0.5 g (0.0037 mole) of 6H-1,2,4-oxadiazin-3(2H)-one-5(4H)-thione dissolved in 10 ml of dry freshly distilled dioxane is added 0.34 g (0.0039 mole) of morpholine. After stirring at room temperature for 17 hours, the solution is filtered, washed with chloroform and dried to give a yield of 0.5 g (74 percent) of 5-(4-morpholinyl)-6H-1,2,4-oxadiazin-3(2H)-one.

後処理

  1. dry with materialof dry freshly distilled dioxane
  2. filtrationthe solution is filtered
  3. washwashed with chloroform
  4. customdried

出典と根拠

ORDレコード
ord-69bf99f35d254cb9821eb00fe8bf4757
出典データセット
uspto-grants-1984_07
特許番号
US04459403

反応ノート

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