Phosphorus oxychloride → Ethyl 2-[2-phenyl-5-(2-thienyl)-4-oxazolyl]acetate
反応式
[C:1]([NH:9][CH:10]([C:17]([C:19]1[S:20][CH:21]=[CH:22][CH:23]=1)=[O:18])[CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.P(Cl)(Cl)(Cl)=O>CN(C)C=O>[C:2]1([C:1]2[O:18][C:17]([C:19]3[S:20][CH:21]=[CH:22][CH:23]=3)=[C:10]([CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])[N:9]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
1.5 g of ethyl 3-benzoylamino-3-(2-thienylcarbonyl)propionate, 10 ml of dimethylformamide and 0.5 g of phosphorus oxychloride are treated in the same manner as described in Example 1. 1.1 g of ethyl 2-[2-phenyl-5-(2-thienyl)-4-oxazolyl]acetate are thereby obtained.
出典と根拠
- ORDレコード
- ord-1678c5d1ad4741a1acf0e4f1be46ec07
- 出典データセット
- uspto-grants-1984_07
- 特許番号
- US04460596
反応ノート
読み込み中…