関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Formamide | HCID 713 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | 3-amino-5-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile | HCID 22346784 | — |
| 生成物 | HCID 178508717 | HCID 178508717 | — |
反応手順
3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole (29.5 g) is suspended in formamide (300 mL) and heated under nitrogen at 180° C. for 4 hours. The reaction mixture is cooled to 30° C. and water (300 mL) is added. The solid is collected, washed well with water, then with methanol and dried in air to give of 4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07732454B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-46acf40008f140e4a1df8f0c57cd1dd8 |
|---|
| 出典メモ | uspto-grants-2010_06 |
|---|
