HCID 11805918、化合物 → Flavan
反応式
[O:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(O)(=O)C.[C].[Pd]>[O:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1参加物
4
実験手順
The flav-3-ene was catalytically hydrogenated in acetic acid (60 ml) using 10% palladium carbon catalyst (150 mg) at room temperature and a atmospheric pressure. 750 ml hydrogen was absorbed over 3 hr. The reaction mixture was filtered, diluted with water, extracted with toluene, and the evaporated extract chromatographed on neutral alumina, eluting with toluene. The product was recrystallised from ethanol yielding flavan (2.75 g) m.pt. 43°-44° C.
後処理
- customat room temperature
- custom750 ml hydrogen was absorbed over 3 hr
- filtrationThe reaction mixture was filtered
- additiondiluted with water
- extractionextracted with toluene
- extractionthe evaporated extract
- customchromatographed on neutral alumina
- washeluting with toluene
- customThe product was recrystallised from ethanol
出典と根拠
- ORDレコード
- ord-e163519bfdc04366996388da1b5f07d7
- 出典データセット
- uspto-grants-1984_07
- 特許番号
- US04461907
反応ノート
読み込み中…