N-Methylethylenediamine → HCID 178480592、化合物

HRID 1464035ノート

反応式

HRID 1464035 の反応式
I.[C:2]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9](=N)SC.[CH3:19][NH:20][CH2:21][CH2:22][NH2:23].[C:24]([OH:31])(=[O:30])/[CH:25]=[CH:26]/[C:27]([OH:29])=[O:28]>C(O)C.CO>[C:24]([OH:31])(=[O:30])/[CH:25]=[CH:26]/[C:27]([OH:29])=[O:28].[CH3:19][N:20]1[CH2:21][CH2:22][NH:23][C:9]1=[N:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

参加物

6

反応物 3

HCID 8014N-MethylethylenediamineHCID 444972Fumaric AcidHCID 178503972HCID 178503972、化合物

生成物 1

HCID 178480592HCID 178480592、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 887Methanol溶媒

実験手順

A mixture of 1-(2-biphenylyl)-2-methyl-2-thiopseudourea hydriodide (5.6 g) and N-methylethylenediamine (3.3 g) in ethanol (70 ml) was heated under reflux for 48 hours. Removal of the solvent gave an oil which was dissolved in methanol (25 ml) and treated with fumaric acid (1.7 g) to give 2-(1-methyl-2-imidazolidinylideneamino)biphenyl fumarate (m.p. 168°-169° C.) which was recrystallised from a 1:1 mixture of methanol and ether.

後処理

  1. temperaturewas heated
  2. temperatureunder reflux for 48 hours
  3. customRemoval of the solvent
  4. customgave an oil which

出典と根拠

ORDレコード
ord-eac13c1931e74b5b968f4925da3563c3
出典データセット
uspto-grants-1994_04
特許番号
US05302720

反応ノート

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