1-Bromooctane → 1-Hydroxy-3-octoxyxanthone

HRID 1464684

反応式

HRID 1464684 の反応式
[OH:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[O:7][C:6]=2[CH:5]=[C:4]([OH:17])[CH:3]=1.C([O-])([O-])=O.[K+].[K+].Br[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]>C(C(C)=O)C>[OH:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[O:7][C:6]=2[CH:5]=[C:4]([O:17][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH:3]=1

参加物

5

反応物 3

HCID 81401-BromooctaneHCID 11430Potassium CarbonateHCID 54881931,3-Dihydroxy-xanthone

生成物 1

HCID 190871431-Hydroxy-3-octoxyxanthone

試薬・触媒・溶媒 1

HCID 6569Methyl Ethyl Ketone溶媒

実験手順

22.8 g of 1,3-dihydroxyxanthone (prepared according to Grover, J. Chem. Soc. 1955, 3982) together with 15.2 g of K2CO3 and 21.2 g of 1-bromooctane are refluxed for 15 hours in 250 ml of methyl ethyl ketone. The salt is isolated by filtration from the cooled reaction mixture and the methyl ethyl ketone solution is concentrated by evaporation under vacuum. Recrystallisation of the residue from heptane gives 1-hydroxy-3-octoxyxanthone with a melting point of 98° C.

後処理

  1. customThe salt is isolated by filtration from the cooled reaction mixture
  2. concentrationthe methyl ethyl ketone solution is concentrated by evaporation under vacuum
  3. customRecrystallisation of the residue from heptane

出典と根拠

ORDレコード
ord-b08f62c80f224e89b0d45a0b3b018ae2
出典データセット
uspto-grants-1994_04
特許番号
US05306829

関連ノート

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