Carbon Dioxide → 1-Chloro-2,6-dimethylbenzene

HRID 1464707

反応式

HRID 1464707 の反応式
[Cl-:1].[Al+3].[Cl-].[Cl-].ClC(O[C:9]1[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:16])=O.C(=O)=O>O>[CH3:16][C:10]1[CH:11]=[CH:12][CH:13]=[C:14]([CH3:15])[C:9]=1[Cl:1]

参加物

5

反応物 3

HCID 280Carbon DioxideHCID 2716182,6-Dimethylphenyl carbonochloridateHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 328851-Chloro-2,6-dimethylbenzene収率 64%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
200 °C

実験手順

0.8 g of anhydrous aluminium chloride was added to 50 g of 2,6-dimethylphenyl chloroformate and the mixture was heated to 200° C. at normal pressure. The evolution of carbon dioxide started above 180° C. and finished after 3.5 hours. The reaction mixture was then cooled, water was added, the organic phase was separated off, the aqueous phase was extracted with methylene chloride, the organic phase which had been separated off was combined with the methylene chloride phase and the combined phases were dried over sodium sulphate and distilled under vacuum. 2,6-Dimethylchlorobenzene was obtained in a yield of 64%.

後処理

  1. customstarted above 180° C.
  2. temperatureThe reaction mixture was then cooled
  3. customthe organic phase was separated off
  4. extractionthe aqueous phase was extracted with methylene chloride
  5. customthe organic phase which had been separated off
  6. dry with materialthe combined phases were dried over sodium sulphate
  7. distillationdistilled under vacuum

出典と根拠

ORDレコード
ord-31819785ed604849af2501da0146c204
出典データセット
uspto-grants-1994_04
特許番号
US05306849

関連ノート

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