o-Cumenyl chloroformate → Benzene, 1-chloro-2-(1-methylethyl)-

HRID 1464712ノート

反応式

HRID 1464712 の反応式
[Cl-:1].[Al+3].[Cl-].[Cl-].ClC(O[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH:15]([CH3:17])[CH3:16])=O>>[CH:15]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[Cl:1])([CH3:17])[CH3:16]

参加物

3

反応物 2

HCID 6365464o-Cumenyl chloroformateHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 16377Benzene, 1-chloro-2-(1-methylethyl)-収率 20%

反応条件

温度
200 °C

実験手順

0.35 g of anhydrous aluminium chloride was added to 25 g of 2-isopropylphenyl chloroformate and the mixture was heated at 200° C. for 3 hours at normal pressure. The reaction mixture was cooled and worked up as described in Example 1. 2-Isopropylchlorobenzene was obtained in a yield of 20%, which is considerable despite the unfavourable substitution pattern.

後処理

  1. temperatureThe reaction mixture was cooled

出典と根拠

ORDレコード
ord-0c4624d1938140769baec1ebe948d82c
出典データセット
uspto-grants-1994_04
特許番号
US05306849

反応ノート

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