Ethanol → 3-(2-Oxo-propylsulfanyl)-benzoic acid ethyl ester

HRID 1466821ノート

反応式

HRID 1466821 の反応式
[O:1]=[C:2]([CH3:14])[CH2:3][S:4][C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([OH:10])=[O:9].OS(O)(=O)=O.[CH2:20](O)[CH3:21]>>[CH2:20]([O:9][C:8](=[O:10])[C:7]1[CH:11]=[CH:12][CH:13]=[C:5]([S:4][CH2:3][C:2](=[O:1])[CH3:14])[CH:6]=1)[CH3:21]

参加物

4

反応物 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 667650833-(2-Oxo-propylsulfanyl)-benzoic acid

生成物 1

HCID 667651013-(2-Oxo-propylsulfanyl)-benzoic acid ethyl ester

実験手順

3-(2-Oxo-propylsulfanyl)-benzoic acid from the previous reaction was dissolved in ethanol and a catalytic amount of conc. H2SO4 was added. The reaction was monitored by analytical TLC and when it was complete the reaction was concentrated to dryness and the resulting residue was purified via silica gel chromatography to give the title compound.

後処理

  1. concentrationwas concentrated to dryness
  2. customthe resulting residue was purified via silica gel chromatography

出典と根拠

ORDレコード
ord-9d8e3d678b22485cadca128bc1209fc9
出典データセット
uspto-grants-2015_04
特許番号
US09000025B2

反応ノート

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