4-Bromo-1-ethyl-1H-pyrazole → 3-[6-Chloro-2-methyl-1-(1-ethyl-1H-pyrazol-4-yl)-1H-indol-3-ylsulfanyl]-2-methyl-benzoic acid ethyl ester

HRID 1466861ノート

反応式

HRID 1466861 の反応式
[CH2:1]([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:20]3[C:15](=[CH:16][C:17]([Cl:21])=[CH:18][CH:19]=3)[NH:14][C:13]=2[CH3:22])[C:6]=1[CH3:23])[CH3:2].Br[C:26]1[CH:27]=[N:28][N:29]([CH2:31][CH3:32])[CH:30]=1>>[CH2:1]([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([S:11][C:12]2[C:20]3[C:15](=[CH:16][C:17]([Cl:21])=[CH:18][CH:19]=3)[N:14]([C:26]3[CH:27]=[N:28][N:29]([CH2:31][CH3:32])[CH:30]=3)[C:13]=2[CH3:22])[C:6]=1[CH3:23])[CH3:2]

参加物

3

反応物 2

HCID 125652014-Bromo-1-ethyl-1H-pyrazoleHCID 667648843-(6-Chloro-2-methyl-1H-indol-3-ylsulfanyl)-2-methyl-benzoic acid ethyl ester

生成物 1

HCID 667652443-[6-Chloro-2-methyl-1-(1-ethyl-1H-pyrazol-4-yl)-1H-indol-3-ylsulfanyl]-2-methyl-benzoic acid ethyl ester

実験手順

Prepared according to the procedure described in Example 42, Step 4, using the following starting materials: 3-(6-chloro-2-methyl-1H-indol-3-ylsulfanyl)-2-methyl-benzoic acid ethyl ester and 4-bromo-1-ethylpyrazole.

後処理

  1. customPrepared

出典と根拠

ORDレコード
ord-f8a1616b72424b5b8c43d1345bb4100e
出典データセット
uspto-grants-2015_04
特許番号
US09000025B2

反応ノート

読み込み中…