m-Chlorophenylhydrazine hydrochloride → 3-(3-Bromo-4-fluoro-phenylsulfanyl)-6-chloro-2-methyl-1H-indole

反応式

[Br:1][C:2]1[CH:3]=[C:4]([S:9][CH2:10][C:11](=O)[CH3:12])[CH:5]=[CH:6][C:7]=1[F:8].Cl.[Cl:15][C:16]1[CH:17]=[C:18]([NH:22]N)[CH:19]=[CH:20][CH:21]=1>>[Br:1][C:2]1[CH:3]=[C:4]([S:9][C:10]2[C:19]3[C:18](=[CH:17][C:16]([Cl:15])=[CH:21][CH:20]=3)[NH:22][C:11]=2[CH3:12])[CH:5]=[CH:6][C:7]=1[F:8]

参加物

反応物 2

HCID 75331m-Chlorophenylhydrazine hydrochloride

HCID 667645651-(3-Bromo-4-fluorophenylthio)propan-2-one

生成物 1

HCID 667655263-(3-Bromo-4-fluoro-phenylsulfanyl)-6-chloro-2-methyl-1H-indole

実験手順

Prepared according to the procedure described in Example 2, Step 1, using the following starting materials: 1-(3-Bromo-4-fluoro-phenylsulfanyl)-propan-2-one and 3-chlorophenylhydrazine hydrochloride.

後処理

customPrepared

出典と根拠

ORDレコード: ord-3c86906e8d91432b8380e1d0107489f1
出典データセット: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09000025B2

反応ノート

読み込み中…