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3-Hydroxybenzoic Acid → Ethyl 4-amino-5-((1-(3-hydroxybenzoyl)piperidin-3-yl)methoxy)-2-methylquinoline-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Hydroxybenzoic Acid | HCID 7420 | — |
| 反応物 | Ethyl 4-amino-2-methyl-5-(piperidin-3-ylmethoxy)quinoline-3-carboxylate | HCID 66746012 | — |
| 生成物 | Ethyl 4-amino-5-((1-(3-hydroxybenzoyl)piperidin-3-yl)methoxy)-2-methylquinoline-3-carboxylate | HCID 66746557 | — |
反応手順
Prepared as in Example 24a from ethyl 4-amino-2-methyl-5-(piperidin-3-ylmethoxy)-quinoline-3-carboxylate (Example 110b) and 3-hydroxybenzoic acid as a white solid (34%). MS 464 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09000054B2 |
| 出典データセット | uspto-grants-2015_04 |
| ORD ID | ord-034a6e697e7c4595ba6e77becc5ca307 |
| 出典メモ | uspto-grants-2015_04 |