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5-(Methylsulfonyl)-1H-indole → tert-Butyl-4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl) methoxy)piperidine-1-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-(Methylsulfonyl)-1H-indole | HCID 14973230 | — |
| 反応物 | tert-Butyl 4-((6-chloropyridin-3-yl)methoxy)piperidine-1-carboxylate | HCID 45786862 | — |
| 生成物 | tert-Butyl-4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl) methoxy)piperidine-1-carboxylate | HCID 67615679 | — |
反応手順
The title compound was prepared by following a procedure described in Intermediate-27 by using tert-butyl 4-((6-chloropyridin-3-yl)methoxy)piperidine-1-carboxylate and 5-(methylsulfonyl)-1H-indole (0.410 g, 27.70%); MS: 386.32 (M−100).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09000175B2 |
| 出典データセット | uspto-grants-2015_04 |
| ORD ID | ord-38c463916d614b81a2ef8995c6eb05bd |
| 出典メモ | uspto-grants-2015_04 |